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Possible side effects include skin irritation, dizziness, headache, racing heartbeat, and rarely nicotine overdose

Analogous to that of endogenous small RNA, the biogenesis of vsiRNA requires not only Dicer-like (DCL) especially DCL4 which processes the viral dsRNA transcript into primary vsiRNA 21, 22 but also (RNA- dependent RNA polymerase (RDR) and Argonaute (AGO) which produced secondary vsiRNA through amplification 23,24,25

The next time youre walking along a busy road or city street, take a look around you cigarette butts are everywhere