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Women with unknown or an unstated status of cigarette smoking in any trimester of pregnancy were classified as no valid smoking status and were excluded from the study

The proportion of non-daily smokers who mainly/exclusively smoked hand-rolled cigarettes increased considerably (from 22.7% in 20062009 to 43.8% in 20212024)

Toxic mechanism Nicotine binds stereoselectively to nicotinic acetylcholine receptors (nAchRs), which are pentameric ligand-gated ion channels (LGICs), localised in the peripheral and central nervous system, autonomic ganglia, sympathetic and parasympathetic nervous system, and skeletal neuromuscular junctions 10 , 23

It looks like, well, a smoke alarm