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One study found a significant link between chronic nicotine use and reduced testosterone levels, contributing to lower libido and less satisfying sexual function

2003;142(11) Hebrew

These may include digestive and nervous signs, such as: Hypersalivation Vomiting Diarrhea Agitation, followed by depression Muscle tremors Incoordination (wobbly walking) Seizures Rapid breathing Bluish gums Dilated pupils Rapid heart rate High blood pressure Cardiac arrest In severe poisoning, dogs' skeletal muscles can paralyze, which will cause respiratory arrest and death