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Within 24-48 hours fluid-filled bullae form, which rupture easily, leading to a diffuse exfoliation (peeling) of the epidermis Refer to the chapter Staphylococcal scalded skin syndrome Viral infection Herpes zoster (figures 16-17) Patients normally have preceding pain Closely grouped red papules, rapidly becoming vesicular and then pustular, develop in a continuous or interrupted band in the area of one or occasionally two and, rarely, more contiguous dermatomes Lesion can become bullous and necrotic Immunosuppressed patients can develop widespread zoster Refer to the chapter Herpes zoster Herpes simplex (figures 18-19) Patients normally have preceding tingling, itching or burning Most commonly affects the mouth and genitalia, although any site can be affected Morphologically the rash consists of small, closely grouped vesicles on a red base Eczema herpeticum - causes clustered vesicles / punched-out monomorphic erosions, which may coalesce