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Keto(iso)leucine was identified as overlapping peaks of 3-methyl-2-oxopentanoate and 4-methyl-2-oxopentanoate in our detection system

Our study is first to demonstrate novel molecular mechanisms involved in the sensitization of PTC cells to ferroptosis inducer- we show that RSL3, a potent direct GPX4 inhibitor, effectively reduces the viability of thyroid cancer lines with various mutational backgrounds compared to HThF control cell line in a dose-dependent manner

The application of HPP has some limitations, including batch operation and high infrastructure costs, ranging from 0.6 to 4 million USD, which account for 7580% of the initial investment [184]

Its structure can therefore be written as H-Ala-Glu-Asp-Gly-OH