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If osmotic and stool-softening options prove insufficient, discuss prescription options like linaclotide (Linzess) or plecanatide (Trulance) with your healthcare providerthese are gut-selective agents that may be safer in GLP-1 users than older stimulants

By performing a genome-wide activation screen, they discovered a group of genes antagonize ferroptosis, including guanosine triphosphate (GTP) cyclohydrolase-1 (GCH1) and its metabolic derivatives BH4/BH2

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