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It sounds a cautionary note for short-term use without a more comprehensive approach to weight management. Overeating far more likely Adam Collins, associate professor of nutrition at the University of Surrey in England, who was not involved in the study, called the paper timely and important. Collins underlined that weight regain is a common issue in all weight loss interventions, but the paper shows that this problem is amplified with GLP-1 medications

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However, there was no clear explanation for the neutral cardiovascular profile of lixisenatide, rather than the expected cardioprotective effect

Each patient underwent a median nerve conduction study, the Boston Carpal Tunnel Questionnaire (BCTQ) and the Neuropathic Pain Symptom Inventory (NPSI)