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[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Griffith O.W., Bridges R.J., Meister A

Research has shown that stress and depression are associated with reduced neurogenesis in the hippocampus, which contributes to the cognitive deficits and mood disturbances characteristic of this disorder

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Regular alcohol use thus leads to overproduction of ROS, triggering lipid peroxidation, and lowering SOD antioxidant activity and reducing GSH levels