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The key recommendations of the updated Guideline, Treating Tobacco Use and Dependence: 2008 Update, based on the literature review and expert Panel opinion, are as follows: Ten Key Guideline Recommendations: The overarching goal of these recommendations is that clinicians strongly recommend the use of effective tobacco dependence counseling and medication treatments to their patients who use tobacco, and that health systems, insurers, and purchasers assist clinicians in making such effective treatments available

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We also categorized serum cotinine levels in tertiles and repeated analyses accordingly