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In order to address this gap in the research, the researchers report, The aims of the present analysis were to use data from clinical practice to assess (1) the association between baseline level of depression and 1-year smoking abstinence and (2) change in depression from baseline to 1-year follow-up in those who achieved abstinence. The researchers conducted an observational study, collecting data from 3,380 patient at the Center for Tobacco Dependence at General University Hospital in Prague