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Human olfactory receptors detect smells when the concentration of these molecules in the air reaches a certain threshold

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95 Mitochondrial depolarization induced by CCCP disrupts the interaction between MGRN1 and GP78, prevents ubiquitination and degradation of GP78 and leads to high GP78 levels, which ubiquitinates MFN1 to promote mitochondrial fission and subsequent mitophagy (Fig