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[13] These findings are further reinforced by pharmacovigilance data from the FDA Adverse Event Reporting System (FAERS) database (n=48,214 reports), where GLP-1RA-related gastrointestinal adverse events, including nausea (9651 vs 38,030) and vomiting (4383 vs 17,062), were lower with combination therapy compared to GLP-1RA monotherapy, suggesting improved tolerability when metformin is added

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Exposure to environmental pollutants, such as heavy metals, pesticides, endocrine-disrupting chemicals (EDCs), and air pollution, has been strongly associated with impaired sperm parameters and hormonal imbalances (16)

Weekly injections may be all it takes for some people to feel better, while others may need more frequent dosing to feel their best