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Common side effects include: Nausea and vomiting Digestive issues like diarrhoea, constipation, or abdominal pain Headaches and fatigue Injection site reactions Serious but less common side effects: Pancreatitis Gallbladder problems Kidney problems Low blood sugar Most gastrointestinal side effects settle within the first month or two

For example, ET patients often have subtle cerebellar ataxia manifested by difficulty in tandem gait [187], and a subset of ET patients will eventually develop frank ataxia [188]

Natural products are promising multitarget agents because of their ability to interact with multiple molecular targets

Witchel SF, Oberfield SE, Pea AS