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The open field test, conducted immediately after injection, indicated that only the DNC + NIC treatment showed an increased effect (** p 0.05) effect on locomotor activities (Figure 2C)

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In addition to the criteria established within organ systems, family history (1st-degree relative with Marfan syndrome) and genetic history (presence of the FBN1 mutation known to cause Marfan syndrome) are considered major criteria

Still, survey participants including former smokers, current smokers and people who had never smoked consistently ranked Natural American Spirit as less harmful to health and the environment