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It has been recognized that impaired mitochondrial structural and functional integrity accompanied by excessive mtROS production is associated with enhanced programmed cell death (PCD) and cellular senescence during COPD pathogenesis, especially in the setting of altered mitophagic degradation [14, 19, 21, 22, 58] (Table 1)
For someone whos a heavy drinker, quitting alcohol, or simply cutting back, can cause life-threatening alcohol withdrawal
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