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Longtime casting director Risa Bramon Garcia, making her directorial debut, exhibits a fine hand with her actors--she succeeds in making Courtney Love a believably insecure firebrand who when drunk sings along to "Through the Eyes of Love"--but trips herself up by diluting her characters' misadventures

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Moreover, the expression of -catenin and Snail1 is up-regulated in the airway wall of both smokers and COPD, and their expression was strongly associated with typical EMT biomarkers (S100A4) and airway obstruction [17, 115]