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vagus nerve efferents and microbiota While "afferent" effects dominate, "efferent vagal" activity also indirectly shapes the microbiota, impacting gastrointestinal motility, acid secretion and bile flow, mucosal immune regulation, and the anti-inflammatory reflex (cholinergic anti-inflammatory pathway, thereby proving that vagal tone influences microbial ecology

Long-term use of popular weight-loss drugs like Ozempic and Wegovy could put some patients at an elevated risk for a potentially fatal gastrointestinal condition that requires surgery, researchers out of China contend in a newly published journal article

Called Wegovy HD, the higher-dose drug helped participants in a study lose about 19% of their body weight, or almost 47 pounds, versus about 16% of body weight, or 39 pounds with the lower dose over almost 17 months

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