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The ACC consensus explicitly states that prospective studies show post-cessation weight gain does not attenuate the cardiovascular benefits of tobacco abstinence [1]

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Likewise, in murine macrophages, the activated 7nAChR can mediate Jak2-STAT3 activation and then can induce the phosphorylation of STAT3, which subsequently downregulates pro-inflammatory cytokines (e.g., IL6, IL12, and TNF-) [133]

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