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Long-term exposure can lead to more serious conditions, including reduced lung function and heart disease

First, tobacco smoke enters the bloodstream and binds to red blood cells, preventing oxygen from reaching the muscles and other body tissues

CVD risks were elevated at almost all levels of current smoking intensity examined and increased with smoking intensity, with HRs for total CVD mortality in current versus never smokers of 1.92 (1.113.32) and 4.90 (3.796.34) for 46 and 25 cigarettes/day, respectively

Majority of workers that experienced symptoms worked in the tobacco fields, where they encountered plants wet from prior rainfall or dew