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In a fluorescein isothiocyanate (FITC)-induced AD mouse model, formononetin was observed to improve E-cadherin localization, suppress the expression of TSLP and IL-33, reinforce the epidermal barrier integrity, and attenuate immune activation (Li et al., 2018)

Moreover, we provide evidence for the carnitine shuttle and carnitine acetyltransferase (CrAT) as a substantial pathway to transfer two-carbon units from mitochondria to cytosol independent of ACLY

Wu R, Zhu G, Ju Y, et al

doi: 10.3389/fncel.2025.1601366 Received 27 March 2025 Accepted 10 June 2025 Published 04 July 2025 Volume 19 - 2025 Edited by Marco Cambiaghi, University of Verona, Italy Reviewed by Enoch Luis, National Council of Science and Technology (CONACYT), Mexico Mingzi Zhang, University of Southern California, United States Updates Copyright 2025 Bessetti and Litwa