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The cellular consequence is increased eumelanin synthesis, documented in the B16-F10 (murine melanoma), MNT-1 (human melanoma), and primary human melanocyte cultures

1 Introduction Affecting an estimated 610% of women of reproductive age, endometriosis (EMS) is a common gynecological disorder that significantly impacts physical and mental health, often manifesting as a debilitating clinical syndrome of chronic pelvic pain, severe dysmenorrhea, dyspareunia, and associated infertility (1)

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