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Baseline characteristics of included individuals Before matching, the combination (GLP-1RA + SGLT2i) and monotherapy (SGLT2i) groups showed significant differences (Table 1)

Whole blood and serum clinical safety markers Whole blood and serum samples were outsourced to an independent commercial laboratory for analysis (Quest Diagnostics, Waco, TX)

However, these do not accurately represent healthy pre-pathological conditions and are unlikely to add support to the ability of GGC to bypass feedback inhibition of GCL

For instance, extracts from Swertia chirata exhibited a high percentage of inhibition in linoleic acid oxidation, comparable to that of BHT, emphasizing the potential of natural antioxidants in food preservation and health applications (Naqvi et al., 2013