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In some people, especially those with light skin, a change in the shape of moles, new moles, and skin cancer, have all occurred in people using melanotan

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Immunofluorescence was performed using the following primary antibodies: CD3 (Abcam), CD8 (Abcam), E-cadherin (Invitrogen), Pan-citokeratin (Invitrogen), alpha-SMA (Invitrogen), P4HA1 (Abcam), and Hydroxyproline (Cell signaling)