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Briefly, 5 L serum (after tenfold dilution with saline) was added to the total reaction system containing GSSG, NADPH and DTNB (5,5-dithiobis-(2-nitrobenzoic acid)

Although nerve conduction studies or somatosensory evoked potentials can identify abnormalities when the spinal MRI appears normal, their clinical utility in elderly patients is limited, and prompt empirical treatment with vitamin B12 is generally preferable to invasive diagnostic testing

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