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A prospective, singlecenter study examined 56 symptomatic HFpEF patients stratified by left ventricular ejection fraction (LVEF) into two cohorts: one with LVEF between 50 and 60% and another with LVEF greater than 60%

70 In addition, a clinical trial in 20 individuals with tinnitus found supplementing with CoQ10 (300 mg per day of ubiquinone formulated with ethyl alcohol and lecithin) for 12 weeks led to reductions in scores on a tinnitus questionnaire in a subset of participants whose blood CoQ10 levels were low at the beginning of the trial

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The KLVFF peptide, recognized for its ability to specifically bind A and inhibit its aggregation, has been successfully incorporated into various nanoformulations [117]