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The search yielded 142 studies, of which 14 were included

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After rising sharply during the COVID-19 pandemic, drug overdose deaths involving opioids declined to 83,140 in 2023, followed by a significant drop to 54,743 deaths in 2024, according to provisional data from the Centers for Disease Control and Prevention

A multicenter, 16-week, double-blind, placebo-controlled study in children and adolescents with PWS and obesity found that liraglutide had no impact on BMI in children or adolescents after 16 weeks of treatment, nor was weight improved after 52 weeks on the drug compared to placebo