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36 , e3218 (2020)

The gauge, or thickness, of the needle also plays a role

In a controlled study by Samsom and colleagues, healthy subjects given pramlintide showed gastric-emptying half-times that lengthened from about 112 minutes on placebo to roughly 169 minutes at 30 g and 177 minutes at 60 g a delay of more than an hour at the higher dose