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FDA labeling for stimulants recommends assessing for cardiac disease before starting therapy and monitoring vital signs

Octreotide (FCFWKTCT) is a somatostatin analog that binds to SSTR2 and SSTR5 and serves as a growth hormone, insulin, and glucagon inhibitor 122

While curcumin supplementation in dogs appears to significantly reduce the expression of genes associated with inflammation, 53 its overall effect on pain and mobility in dogs with osteoarthritis has produced variable results, exhibiting improvements in subjective pain assessments in some cases of dogs with osteoarthritis, but not exhibiting reliable objective improvements in mobility