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Glucagon-like peptide-1 is a hormone your gut produces naturally after eating

How GLP-1 Receptors Work For example, in the liver, the activation of the GLP-1 receptor reduces fat accumulation through inhibiting fatty acid synthesis and enhancing insulin signaling to boost glucose uptake and tamp down glucose production, with the end result of lowering blood glucose and ridding the liver of fat

About this article Cite this article Taheri, M., Ghafouri-Fard, S., Najafi, S

The doses of GLP-1 provided by semaglutide and tirzepatide are far greater than the body would naturally expect to receive, he says, which may suppress the body's ability to secrete GLP-1 on its own