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The trend recently caught the attention of the FDA, which has added more than two dozen peptides to an interim list of substances that should not be compounded due to safety concerns

Blood samples were collected at regular intervals to measure acetaldehyde levels over the course of three hours

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Across platforms, metabolite measurements demonstrated consistent cross-platform behavior, with 50% of metabolites showing both high correlation and quantitative agreement, and a smaller subset (7%) exhibiting strong correlation but systematic differences in absolute quantification ( Figure S1E)