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STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum

Myristoylation of FSP1 is crucial for the inhibition of ferroptosis (Bersuker et al., 2019) because it reduces CoQ10 to prevent lipid oxidation (Bersuker et al., As an essential intracellular antioxidant, reduced glutathione (-L-glutamyl-L cysteinylglycine, GSH) synthesis requires the cystine/glutamate antiporter system (encoded by SLC7A11 ) to import cystine from the environment and reduce it to cysteine