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Peripherally, they primarily act on the pancreas and gastrointestinal tract, stimulating insulin secretion and inhibiting glucagon secretion when blood glucose levels rise, thereby exerting a hypoglycemic effect [60]

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However, their effectiveness lacks strong evidence, with exceptions for cases where autoimmune hepatitis (AIH) cannot be ruled out or for DILI caused by immune-checkpoint inhibitors (ICIs) that are used in the treatment of cancer ( Fig

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