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Sermorelin and Tesamorelin have extremely short half-lives of roughly 1126 minutes because they are minimally modified growth hormone-releasing hormone analogs that are rapidly cleaved by dipeptidyl peptidase-4 and other serum proteases

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As both neuroinflammation and oxidative stress or metabolic dysregulation are prevalent across the epilepsies, which are both argued to be causal and consequential to the disease, the direct interactions between neuroinflammation and oxidative stress are key components of disease pathology which deserve further evaluation

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