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doi: 10.1074/jbc.M110.118620

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In native physiology, the six IGFBPs perform several overlapping regulatory jobs: they extend the circulating half-life of IGF-1, they create a reservoir of hormone that can be released as needed, they modulate the amount of free peptide available to receptors, and in some contexts they exert IGF-independent effects of their own

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WBCILs stabilization strategies maintain vesicle integrity during storage and formulation, ensuring consistent high vitamin C delivery across product formats

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