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These models are not perfect analogs for human androgenetic alopecia rodent hair cycling differs from human cycling in important ways but they establish that the in-vitro effects translate to a living organism rather than being artifacts of the cell-culture environment.5 Mechanistic Research: Gene Expression And Signaling One of the more interesting bodies of research on GHK-Cu involves whole-genome expression analysis studies that examine which genes are upregulated or downregulated in cells exposed to the peptide
Entry into cells occurs predominantly through ZIP family members located on the plasma membrane, which mediate zinc influx by transporting it from extracellular or vesicular compartments into the cytosol
Nature 355 , 696702 (1992)
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