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Importantly, surface-agnostic in this context refers to a topography-preserving physicochemical reactivation principle rather than equivalent levels of biologic or clinical evidence across all materials and outcomes

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Materials And Methods Experimental Animals Male C57Bl/6NNIA mice of ages 6 months (young), 12 months (mature adults), and 24 months (old) were obtained from colonies administered by the National Institute on Aging, as described previously [34]