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IGF-1R Receptor Binding and Downstream Signalling Both IGF-1 and des-(1-3)IGF-1 bind only to the type 1 IGF receptor in L6 myoblasts, rat vascular smooth-muscle cells, and human lung fibroblasts, with binding potencies in the order des-(1-3)IGF-1 greater than IGF-1 a difference attributed to the lower affinity of des-(1-3)IGF-1 for the competing IGFBP rather than superior intrinsic receptor affinity

Topical application of Urolithin A slows intrinsic skin aging and protects from UVB-mediated photodamage: Findings from Randomized Clinical Trials D DAmico, AM Fouassier, J Faitg, N Hennighausen, M Brandt, D Konstantopoulos, C Rinsch, A Singh medRxiv 2023.06.16.23291378

With regard to gender, there was a significant negative correlation between estrogen level and serum free carnitine in females (58)

P values of less than 0.05 were considered statistically significant