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19, 71 The diagnosis of malignant blue nevus should be considered when a lesion that has arisen in a pre-existing blue or cellular blue nevus exhibits highly atypical epithelioid melanocyte with bizarre tumor giant cells and numerous abnormal mitotic figures averaging 89 per mm 2

Due to the close connection between this pathogenesis, it must be considered that drug manipulation of one of the diseases can also affect the other components of this interaction