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In order to prevent oxidative stress due to increased intracellular iron and subsequent cell death by ferroptosis, OLs can export iron via FPN that acts in concert with ferroxidases, as evidenced by increased oxidative stress in OLs deficient for hephaestin (54)

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Science 300:14391443 Kuroki F, Matsumoto T, Iida M (2003) Selenium is depleted in Crohns disease on enteral nutrition

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