(1) Because people with type 2 diabetes who start using an SGLT2i or GLP-1 RA will probably delay initiation of another glucose-lowering medication, costs will be saved
Eur J Clin Nutr 72, 105111.CrossRefGoogle ScholarPubMed Gandek, TB, van der Koog, L & Nagelkerke, A (2023) A comparison of cellular uptake mechanisms, delivery efficacy, and intracellular fate between liposomes and extracellular vesicles
Extracellular mtDNA can act as a damage-associated molecular pattern (DAMP), triggering the activation of innate immune receptors such as toll-like receptors (TLRs) and inducing the production of type I interferons (IFNs) [131]
However, it is essential to maintain a balanced perspective, recognising both the potential benefits and the need for continued research and careful medical supervision