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It has been shown to inhibit apoptosis and cell death in primary cardiomyocyte and endothelial cell cultures (352), to have varying effects on the proliferation of various prostate carcinoma cell lines (353), to inhibit isoproterenol-induced lipolysis in rat adipocyte cultures (354), and to induce hypotension and bradycardia when injected into the nucleus tractus solitarii of rats (355)

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This observation underscores the possibility of MGF as a potential agent in enhancing tissue regeneration by modulating cellular mechanisms that may prevent programmed cell death