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However, one study showed that while both of these drugs affect gastric emptying to a similar degree, these effects are much longer lasting with tirzepatide

Because Ozempic helps people eat less, a halt to treatment may lead them to consume more calories and eat larger portions, leading to an increase in blood sugar, Tchang says

Therefore, switching should be considered only after evaluating the patients experience, goals, and tolerance to current treatment

It may also be picking up a real limit: that the sense of feeling better, once weighed against nausea, muscle loss and the burden of a long-term injectable, is smaller and less durable than it looks in the clinic