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In SLE patients, SR-E1 expression is elevated even in early disease onset and low disease activity and correlates with high-sensitivity C-reactive protein (hsCRP), proinflammatory HDL, and oxLDL (108)

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For example, in one clinical trial, hypertensive TT subjects taking 1.6 mg/day of riboflavin (in addition to normal antihypertensive medication) over 16 weeks experienced an average decrease of 5.6 mm/Hg in systolic blood pressure compared to those taking a placebo