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Butyrate, serving as the primary energy source for intestinal epithelial cells, not only maintains colonic barrier function but also alleviates inflammatory responses by inhibiting the NF-B signaling pathway (161, 162)

Studies show that iron-sag markers can be traced in cellular and animal models of neurodegenerative diseases ( in vitro assay, ferroptosis is associated with reduced expression of SLC7A11 and GPX4 proteins, as well as ROS accumulation in corticosterone-constructed hippocampal progenitor neurons (Li E