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As estrogen drops during perimenopause and crashes after menopause, your body composition shifts in ways that make weight management harder

It took me about 3 minutes to find this reference: Phosphotransferase systems involved in microbial processing of carbohydrates also were found to be over expressed in the intestines of obese people, notably from Prevotellaceae I am not saying that carbs increase Prevotella activity or that Prevotella causes heart attacks

To know if Mounjaro is working, keep track of your appetite, blood sugar, and any weight loss you see as time goes on