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When addressing dimeric protein targets, the ability of dimeric therapeutic agents to antagonize paired receptors within a single molecular entity potentially offers superior therapeutic efficacy and target selectivity 15,16

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In addition to their well-known anti-inflammatory effects, EPA and DHA may also have anti-arrhythmic properties, and have been found in multiple studies to benefit heart disease patients by improving lipid levels, lowering blood pressure, and reducing the risk of sudden death (Colussi 2018

Blocking both pathways simultaneously is mechanistically analogous to how bariatric surgery suppresses appetite through multiple concurrent mechanisms