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In human vastus lateralis biopsies, MGF mRNA rose 4.5-fold 2.5 hours after a single bout of resistance exercise compared with pre-exercise baseline, while systemic IGF-1 did not change significantly, suggesting a paracrine rather than endocrine role [13]
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What lipotropic injections plausibly contribute is more modest and more defensible: correction of real deficiencies, a tolerable non-stimulant option for patients who cannot or will not take prescription weight loss medication, and a recurring touchpoint that keeps patients engaged with a supervised program
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