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Elevated endogenous testosterone concentrations potentiate muscle androgen receptor responses to resistance exercise

A combination of GLP-1 receptor agonists and metformin had little effect on menstrual frequency or serum testosterone

It also improves the accumulation of lipid metabolism intermediates (ketone bodies) and low-density lipoprotein, involving 10 key metabolic pathways such as various amino acid biosynthesis and pyruvate metabolism, reversing the metabolic network disorders caused by HAPH at the systemic level (Yang et al., 2021)