Copper has long been associated with the formation of protease-resistant, -sheet enriched scrapie conformation of prion protein PrP Sc , which has been considered the critical step in the neurodegenerative prion diseases known as transmissible spongiform encephalopathies [43, 262]
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Michaels, who rose to fame as a trainer on the controversial weight-loss reality-TV show "The Biggest Loser," argued that the drug, semaglutide, may have unforeseen side effects and that the weight-loss results aren't sustainable
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