how long before glp 1 is out of your system do you have to take GLP-1 for weight loss Does GLP-1 Build Up in

Source: Drucker, D

While the decision to continue other oral antidiabetic drugs or GLP-1 receptor agonists should be made on an individualized basis, they may afford better postprandial control and reduce the insulin requirements, which in turn is associated with a lesser weight gain

Compared with traditional small molecule antidiabetic drugs, peptide-based drugs modified from GLP-1 have a glucose concentration-dependent effect on stimulating insulin secretion

GLP-1 receptor agonist medications like semaglutide injections, while generally well-tolerated, can cause side effects like nausea, vomiting, diarrhea, constipation, and abdominal pain in some people